Ranking Value: 293
| Champion | AJAX ST. LOUIS SC FIRE (MO) |
| Finalist | FALLS CITY FCSC 04G GOLD (KY) |
| Semi-Finalist | GATEWAY RUSH 2004 GIRLS BLUE (IL) |
| Qtr-Finalist | SPORTING SOUTHERN INDIANA SURGE (IN) |
| Teams | MP | W | D | L | GF | GA | PTS |
|---|---|---|---|---|---|---|---|
| AJAX ST. LOUIS SC FIRE (MO) | 3 | 2 | 0 | 1 | 3 | 4 | 6 |
| FALLS CITY FCSC 04G GOLD (KY) | 3 | 2 | 0 | 1 | 5 | 2 | 6 |
| GATEWAY RUSH 2004 GIRLS BLUE (IL) | 3 | 1 | 1 | 1 | 4 | 2 | 4 |
| SPORTING SOUTHERN INDIANA SURGE (IN) | 3 | 0 | 1 | 2 | 3 | 7 | 1 |
| Saturday, November 6, 2021 | ||||
|---|---|---|---|---|
| 8:00 AM | GATEWAY RUSH 2004 GIRLS BLUE | 0 - 1 | FALLS CITY FCSC 04G GOLD | |
| 8:00 AM | AJAX ST. LOUIS SC FIRE | 2 - 1 | SPORTING SOUTHERN INDIANA SURGE | |
| 3:00 PM | SPORTING SOUTHERN INDIANA SURGE | 1 - 1 | GATEWAY RUSH 2004 GIRLS BLUE | |
| 3:00 PM | FALLS CITY FCSC 04G GOLD | 0 - 1 | AJAX ST. LOUIS SC FIRE | |
| Sunday, November 7, 2021 | ||||
| 9:45 AM | GATEWAY RUSH 2004 GIRLS BLUE | 3 - 0 | AJAX ST. LOUIS SC FIRE | |
| 11:30 AM | FALLS CITY FCSC 04G GOLD | 4 - 1 | SPORTING SOUTHERN INDIANA SURGE | |