Ranking Value: 219
| Champion | SPORTING SOUTHERN INDIANA FUSION (IN) |
| Finalist | TENNESSEE UNITED 06 GIRLS BLUE (TN) |
| Semi-Finalist | CUTTERS 05/06 GIRLS RED (IN) |
| Qtr-Finalist | INDIANA SOUTHWEST FC 2005 GIRLS (IN) |
| - | OWENSBORO UNITED 2005 GIRLS (KY) |
| Teams | MP | W | D | L | GF | GA | PTS |
|---|---|---|---|---|---|---|---|
| CUTTERS 05/06 GIRLS RED (IN) | 4 | 1 | 2 | 1 | 3 | 4 | 5 |
| INDIANA SOUTHWEST FC 2005 GIRLS (IN) | 4 | 1 | 0 | 3 | 4 | 10 | 3 |
| OWENSBORO UNITED 2005 GIRLS (KY) | 4 | 0 | 2 | 2 | 1 | 4 | 2 |
| SPORTING SOUTHERN INDIANA FUSION (IN) | 4 | 3 | 1 | 0 | 8 | 2 | 10 |
| TENNESSEE UNITED 06 GIRLS BLUE (TN) | 4 | 2 | 1 | 1 | 7 | 5 | 7 |
| Friday, May 7, 2021 | ||||
|---|---|---|---|---|
| 7:45 PM | SPORTING SOUTHERN INDIANA FUSION | 2 - 0 | OWENSBORO UNITED 2005 GIRLS | |
| Saturday, May 8, 2021 | ||||
| 11:30 AM | SPORTING SOUTHERN INDIANA FUSION | 3 - 2 | TENNESSEE UNITED 06 GIRLS BLUE | |
| 11:30 AM | CUTTERS 05/06 GIRLS RED | 2 - 1 | INDIANA SOUTHWEST FC 2005 GIRLS | |
| 4:45 PM | CUTTERS 05/06 GIRLS RED | 1 - 1 | OWENSBORO UNITED 2005 GIRLS | |
| 4:45 PM | INDIANA SOUTHWEST FC 2005 GIRLS | 2 - 5 | TENNESSEE UNITED 06 GIRLS BLUE | |
| Sunday, May 9, 2021 | ||||
| 8:00 AM | OWENSBORO UNITED 2005 GIRLS | 0 - 0 | TENNESSEE UNITED 06 GIRLS BLUE | |
| 9:45 AM | SPORTING SOUTHERN INDIANA FUSION | 0 - 0 | CUTTERS 05/06 GIRLS RED | |
| 11:30 AM | INDIANA SOUTHWEST FC 2005 GIRLS | 1 - 0 | OWENSBORO UNITED 2005 GIRLS | |
| 1:15 PM | CUTTERS 05/06 GIRLS RED | 0 - 2 | TENNESSEE UNITED 06 GIRLS BLUE | |
| 3:00 PM | SPORTING SOUTHERN INDIANA FUSION | 3 - 0 | INDIANA SOUTHWEST FC 2005 GIRLS | |