Ranking Value: 474
| Champion | CINCINNATI ELITE FC CEFC G2003 (OS) |
| Champion | KINGS HAMMER KHB G03 PREMIER (KY) |
| Finalist | LIVERPOOL FC MI ANN ARBOR 03 G ACADEMY (MI) |
| Finalist | NATIONALS ST CLAIR 03 GIRLS BLACK (MI) |
| Semi-Finalist | MICHIGAN STARS 03G REVOLUTION (MI) |
| Semi-Finalist | SPORTING SOUTHERN INDIANA SURGE (IN) |
| Qtr-Finalist | CINCY SC G03 (OS) |
| Qtr-Finalist | KINGS HAMMER SC KHC G04/03 PREMIER 1 (KY) |
| - | NORTHWEST FC 2003G NWFC ORANGE (OS) |
| - | PRIDE SC SAMBA (OS) |
| Teams | MP | W | D | L | GF | GA | PTS |
|---|---|---|---|---|---|---|---|
| KINGS HAMMER SC KHC G04/03 PREMIER 1 (KY) | 3 | 0 | 2 | 1 | 2 | 3 | 2 |
| KINGS HAMMER KHB G03 PREMIER (KY) | 3 | 3 | 0 | 0 | 4 | 0 | 9 |
| LIVERPOOL FC MI ANN ARBOR 03 G ACADEMY (MI) | 3 | 2 | 0 | 1 | 8 | 6 | 6 |
| MICHIGAN STARS 03G REVOLUTION (MI) | 2 | 1 | 0 | 1 | 4 | 2 | 3 |
| NORTHWEST FC 2003G NWFC ORANGE (OS) | 2 | 0 | 1 | 1 | 4 | 5 | 1 |
| PRIDE SC SAMBA (OS) | 3 | 0 | 1 | 2 | 3 | 9 | 1 |
| Friday, November 12, 2021 | ||||
|---|---|---|---|---|
| 11:30 AM | KINGS HAMMER SC KHC G04/03 PREMIER 1 | 2 - 2 | PRIDE SC SAMBA | |
| 7:50 PM | MICHIGAN STARS 03G REVOLUTION | 0 - 2 | KINGS HAMMER KHB G03 PREMIER | |
| 7:50 PM | LIVERPOOL FC MI ANN ARBOR 03 G ACADEMY | 5 - 4 | NORTHWEST FC 2003G NWFC ORANGE | |
| Saturday, November 13, 2021 | ||||
| 4:20 PM | KINGS HAMMER SC KHC G04/03 PREMIER 1 | 0 - 1 | KINGS HAMMER KHB G03 PREMIER | |
| 4:20 PM | LIVERPOOL FC MI ANN ARBOR 03 G ACADEMY | 3 - 1 | PRIDE SC SAMBA | |
| Sunday, November 14, 2021 | ||||
| 9:40 AM | MICHIGAN STARS 03G REVOLUTION | 4 - 0 | PRIDE SC SAMBA | |
| 11:20 AM | LIVERPOOL FC MI ANN ARBOR 03 G ACADEMY | 0 - 1 | KINGS HAMMER KHB G03 PREMIER | |
| 2:40 PM | NORTHWEST FC 2003G NWFC ORANGE | 0 - 0 | KINGS HAMMER SC KHC G04/03 PREMIER 1 | |
| Teams | MP | W | D | L | GF | GA | PTS |
|---|---|---|---|---|---|---|---|
| CINCINNATI ELITE FC CEFC G2003 (OS) | 3 | 2 | 1 | 0 | 10 | 5 | 7 |
| CINCY SC G03 (OS) | 3 | 0 | 1 | 2 | 2 | 9 | 1 |
| NATIONALS ST CLAIR 03 GIRLS BLACK (MI) | 3 | 2 | 0 | 1 | 9 | 4 | 6 |
| SPORTING SOUTHERN INDIANA SURGE (IN) | 3 | 0 | 2 | 1 | 2 | 5 | 2 |
| Friday, November 12, 2021 | ||||
|---|---|---|---|---|
| 4:30 PM | CINCY SC G03 | 1 - 5 | CINCINNATI ELITE FC CEFC G2003 | |
| 7:50 PM | NATIONALS ST CLAIR 03 GIRLS BLACK | 3 - 0 | SPORTING SOUTHERN INDIANA SURGE | |
| Saturday, November 13, 2021 | ||||
| 1:00 PM | CINCY SC G03 | 1 - 4 | NATIONALS ST CLAIR 03 GIRLS BLACK | |
| 4:20 PM | SPORTING SOUTHERN INDIANA SURGE | 2 - 2 | CINCINNATI ELITE FC CEFC G2003 | |
| Sunday, November 14, 2021 | ||||
| 8:00 AM | CINCINNATI ELITE FC CEFC G2003 | 3 - 2 | NATIONALS ST CLAIR 03 GIRLS BLACK | |
| 1:00 PM | SPORTING SOUTHERN INDIANA SURGE | 0 - 0 | CINCY SC G03 | |