Ranking Value: 486
| Champion | LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G (MO) |
| Finalist | QUAD CITIES RUSH 2009 GIRLS (IL) |
| Semi-Finalist | EAST MOLINE SILVIS EMSSC U13G (IL) |
| Qtr-Finalist | FC AMERICA () |
| - | PEORIA FC UNITED 2009 GIRLS NAVY (IL) |
| Teams | MP | W | D | L | GF | GA | PTS |
|---|---|---|---|---|---|---|---|
| FC AMERICA () | 4 | 0 | 2 | 2 | 2 | 5 | 2 |
| EAST MOLINE SILVIS EMSSC U13G (IL) | 4 | 1 | 1 | 2 | 4 | 7 | 5 |
| LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G (MO) | 4 | 3 | 1 | 0 | 11 | 1 | 13 |
| PEORIA FC UNITED 2009 GIRLS NAVY (IL) | 4 | 0 | 1 | 3 | 1 | 13 | 1 |
| QUAD CITIES RUSH 2009 GIRLS (IL) | 4 | 3 | 1 | 0 | 9 | 1 | 13 |
| Saturday, April 30, 2022 | ||||
|---|---|---|---|---|
| 8:00 AM | EAST MOLINE SILVIS EMSSC U13G | 1 - 1 | FC AMERICA | |
| 9:30 AM | PEORIA FC UNITED 2009 GIRLS NAVY | 0 - 4 | QUAD CITIES RUSH 2009 GIRLS | |
| 2:00 PM | LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G | 1 - 1 | QUAD CITIES RUSH 2009 GIRLS | |
| 3:30 PM | PEORIA FC UNITED 2009 GIRLS NAVY | 0 - 3 | EAST MOLINE SILVIS EMSSC U13G | |
| 5:00 PM | FC AMERICA | 0 - 1 | LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G | |
| Sunday, May 1, 2022 | ||||
| 8:00 AM | QUAD CITIES RUSH 2009 GIRLS | 2 - 0 | EAST MOLINE SILVIS EMSSC U13G | |
| 11:00 AM | QUAD CITIES RUSH 2009 GIRLS | 2 - 0 | FC AMERICA | |
| 2:00 PM | FC AMERICA | 1 - 1 | PEORIA FC UNITED 2009 GIRLS NAVY | |
| 2:00 PM | EAST MOLINE SILVIS EMSSC U13G | 0 - 4 | LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G | |
| 5:00 PM | LOU FUSZ ATHLETIC LFA BLUE STAR MAJOR 2010G | 5 - 0 | PEORIA FC UNITED 2009 GIRLS NAVY | |